Why MAXMIL

Complete Nutrient Support for Every Step of a Mother's Journey. From Family Planning to Breastfeeding.

MAXMIL Pregnant

Pregnancy is not only about growing a baby, but also about supporting the mother who is growing, nurturing, and eventually feeding that baby. From preparing for pregnancy, through the critical months of fetal development, and into breastfeeding, a mother's nutritional needs change, and so does her responsibility for two lives. Research in maternal and child nutrition consistently links inadequate nutrient intake during the reproductive years to impaired fetal growth, a higher risk of neural tube defects, anemia, and even a greater susceptibility to chronic disease later in the child's life. Closing these nutritional gaps early is one of the most meaningful things a family can do for the health of the next generation. MAXMIL® was formulated around this understanding and brings together 18 essential nutrients in one comprehensive formula to complement a mother's daily nutrition throughout this important journey.

MAXMIL Fetal Programming Diagram

Composition of MAXMIL® (per film-coated caplet):

MAXMIL Composition

Table 1. Composition of Maxmil®

1. Preconception: Building the Foundation Before Life Begins

Fertility is a shared biological project between men and women, and nutrition shapes the quality of both contributions. 5-MTHF, Zinc and Vitamin D3 help support the regulation of DNA integrity, healthy cellular function and protection against oxidative stress, important foundations for maintaining reproductive health in both men and women. Adequate nutrition plays an important role in supporting reproductive health and optimizing the conditions for conception in both women and men.

MAXMIL® provides essential nutrients from the beginning of the family-planning journey, helping couples build a strong nutritional foundation for a healthy pregnancy.

2. Pregnancy: Supporting the Most Critical Window of Development

The first trimester is when a baby's vital organs are formed, a process called organogenesis. It is also the period when the developing body is most vulnerable to nutrient shortfalls, with consequences that can range from developmental abnormalities to a higher lifelong risk of chronic disease.

MAXMIL Fetal Development

MAXMIL®'s complete formula of 18 nutrients is designed to support this critical window in several complementary ways:

  • 5-MTHF (active folate), Vitamin B12, and Iron support DNA synthesis, cell division, and the formation of vital organ tissue. Because 5-MTHF is already in its active form, it does not depend on the body's own conversion step the way conventional folic acid does. Clinical studies show it raises blood folate status more effectively than folic acid, while producing markedly less unmetabolized folic acid in the bloodstream. A difference researchers consider clinically reassuring for both mother and baby.
  • Vitamins A, D, and E contribute to healthy cell differentiation and the development of the heart, lungs, and respiratory system.
  • Iodine and Zinc are essential for fetal thyroid hormone production. Thyroid hormone drives neuronal migration and brain maturation, which is why global health bodies recommend increasing iodine intake throughout pregnancy and lactation. Inadequate intake is recognized as the world's leading preventable cause of impaired childhood brain development.
  • DHA accumulates rapidly in the fetal brain and central nervous system during pregnancy, particularly in the third trimester, supporting the structural groundwork for lifelong cognitive and visual function.
  • Coral Calcium, Vitamin K2 (MenaQ7®), Vitamin D3, and Magnesium work together to solve what nutrition scientists call the "calcium paradox": Vitamin D3 increases calcium absorption. At the same time, Vitamin K2 activates the proteins that direct that calcium into bone rather than soft tissue. Together, this combination supports strong maternal bone density while helping build the fetal skeleton, rather than simply adding calcium without directing where it goes.
Calcium Paradox

Figure 1. Maxmil® Prevents the Calcium Paradox

3. Breastfeeding: Continuing the Legacy of Nourishment

Breastfeeding is a remarkable continuation of the mother's journey of nourishment. Breast milk provides the nutrients and bioactive components a baby needs for growth, brain development, and immune function during the earliest months of life. At the same time, a breastfeeding mother continues to have important nutritional needs of her own. MAXMIL® provides 18 essential nutrients to complement her daily nutrition, helping support her well-being during this important stage of motherhood. Because nourishing the baby begins with nourishing the mother.

A Complete Nutritional Companion, From the First Decision to the First Milk

Choosing to prepare for pregnancy and nourish the body throughout pregnancy and breastfeeding is one of the most meaningful steps parents can take toward a healthy beginning. MAXMIL® is designed to support this journey with 18 essential nutrients in one comprehensive, science-informed formula, helping complement a mother’s nutritional needs from preconception through pregnancy and breastfeeding. Therefore, a mother can spend less time worrying about nutritional gaps and more time embracing the moments that matter. Because when a mother is well nourished and well supported, she is better prepared for the remarkable journey of nurturing new life.

Complete ingredients for fetal development

Create great environment for fetal growth

Superior supplementation to support maternal health during pregnancy & breastfeeding

Complete Mom's Daily Nutrition with MAXMIL

One Mother. One Journey. Two Lives to Nourish.

References

  1. A. M. Molloy et al. 2008. Effects of folate and vitamin B12 deficiencies during pregnancy on fetal, infant, and child development. Food and Nutrition Bulletin, vol. 29, no. 2 (supplement) © 2008, The United Nations University.
  2. Araszkiewicz, A. F., Jańczak, K., Wójcik, P., et al. 2025. MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging Clinical Implications—A Review. Genes, 16(4), 441. https://doi.org/10.3390/genes16040441
  3. Ars CL, Nijs IM, Marroun HE, et al. 2019. Prenatal folate, homocysteine and Vitamin B12 levels and child brain volumes, cognitive development and psychological functioning: The Generation R Study. British Journal of Nutrition, 122(s1):S1-S9. doi:10.1017/S0007114515002081
  4. Authors, C., Auton, A., Abecasis, G. R., et al. 2015. A global reference for human genetic variation. Nature, 526(7571), 68–74. https://doi.org/10.1038/nature15393
  5. Avagliano L., Massa V., George TM., et.al. 2019. Overview on Neural tube defects: from development to physical characteristics. Birth Defects Res. 2019 November 15; 111(19): 1455-1467
  6. Bailey SW, Ayling JE. 2018. The pharmacokinetic advantage of 5-methyltetrahydrofolate for minimization of the risk for birth defects OPEN. Scientific Reports, 8:4096. doi:10.1038/s41598-018-22191-2
  7. Barker, D. 2004. The developmental origins of adult disease. Journal of the American College of Nutrition, 23(sup6), 588S-595S. https://doi.org/10.1080/07315724.2004.10719428
  8. Bouhadana D, Godin Pagé, M H, Montjean D. 2025. The Role of Antioxidants in Male Fertility: A Comprehensive Review of Mechanisms and Clinical Applications. Antioxidants (MDPI). doi: 10.3390/antiox14081013
  9. Capra M, E. Bellani A., et.al. 2026. Maternal Nutrition During Pregnancy and Fetal Outcome, Short- and Long-Term Health Effects: A Narrative Review. MDPI. Nutrients 2026, 18, 1375. https://doi.org/10.3390/nu18091375
  10. Cilio S, Renzo M, et. Al 2021. Beneficial Effects of Antioxidants in Male Infertility Management: A Narrative Review. Journal of Clinical Medicine (MDPI).
  11. Clement A, Menezo Y, Cohen M, et al. 2019. 5-Methyltetrahydrofolate reduces blood homocysteine level significantly in C677T methyltetrahydrofolate reductase single-nucleotide polymorphism carriers consulting for infertility. Journal of Gynecology Obstetrics and Human Reproduction, 49(1). doi:10.1016/j.jogoh.2019.08.005
  12. Cochrane KM, Mayer C, Devlin AM, Elango R, Hutcheon JA, Karakochuk CD. 2020. Is natural (6S)-5-methyltetrahydrofolic acid as effective as synthetic folic acid in increasing serum and red blood cell folate concentrations during pregnancy? A proof-of-concept pilot study. Trials, 21(1). doi:10.1186/s13063-020-04320-3
  13. Czarnowska-Kujawska, M., Draszanowska, A., & Gujska, E. 2020. Effect of Different Cooking Methods on Folate Content in Chicken Liver. Foods (Basel, Switzerland), 9(10), 1431. https://doi.org/10.3390/foods9101431
  14. Fallah A, Mohammad-Hasani A, Colagar AH. 2018. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men’s Health, Germination, Sperm Quality, and Fertilization. Journal of Reproduction & Infertility.
  15. Forges T, Monnier-Barbarino P, Alberto JM, Guéant-Rodriguez RM, Daval JL, Guéant JL. 2007. Impact of folate and homocysteine metabolism on human reproductive health. Human Reproduction Update, 13(3):225-238. doi:10.1093/humupd/dml063
  16. Garner TB, Hester JM, Carothers A, Diaz FJ. 2023. The Implications of Insufficient Zinc on the Generation of Oxidative Stress Leading to Decreased Oocyte Quality. Reproductive Sciences.
  17. Gnosis by Lesaffre. 2025. Pregnancy. https://quatrefolic.com/health-benefits/pregnancy/
  18. Gould J F, et al. 2021. The Influence of Prenatal DHA Supplementation on Individual Domains of Behavioral Functioning in School-Aged Children: Follow-Up of a Randomized Controlled Trial. Nutrients 2021, 13, 2996. https://doi.org/10.3390/nu13092996
  19. Henderson AM, Aleliunas RE, Loh SP, et al. 2018. L-5-methyltetrahydrofolate supplementation increases blood folate concentrations to a greater extent than folic acid supplementation in Malaysian women. Journal of Nutrition, 148(6):855-890. doi:10.1093/jn/nxy057
  20. Kubo, Y., et.al. 2020. Distribution of 5-Methyltetrahydrofolate and Folic Acid Levels in Maternal and Cord Blood Serum: Longitudinal Evaluation of Japanese Pregnant Women. Nutrients 2020, 12, 1633; doi:10.3390/nu12061633. www.mdpi.com/journal/nutrients.
  21. Lamers Y, Prinz-Langenohl R, Brämswig S, Pietrzik K. 2006. Red Blood Cell Folate Concentrations Increase More after Supplementation with [6S]-5-Methyltetrahydrofolate than with Folic Acid in Women of Childbearing Age 1-4. American Journal of Clinical Nutrition, 84(1), 156–161. https://doi.org/10.1093/ajcn/84.1.156
  22. Ledowsky, C., Mahimbo, A., Scarf, V., et al. 2022. Women Taking a Folic Acid Supplement in Countries with Mandatory Food Fortification Programs May Be Exceeding the Upper Tolerable Limit of Folic Acid: A Systematic Review. Nutrients, 14(13), 2715. https://doi.org/10.3390/nu14132715
  23. Lockyer F, McCann S, Moore S E. 2021. Breast Milk Micronutrients and Infant Neurodevelopmental Outcomes: A Systematic Review. Nutrients, 2021. Nutrients 2021, 13(11), 3848; https://doi.org/10.3390/nu13113848
  24. Mandatori D., Pelusi L., et al. 2021. The Dual Role of Vitamin K2 in ‘Bone-Vascular Crosstalk’: Opposite Effects on Bone Loss and Vascular Calcification. International Journal of Molecular Sciences / PMC, 2021. Nutrients 2021, 13(4), 1222; https://doi.org/10.3390/nu13041222
  25. Massari M., Novielli C., et al. 2020. Multiple Micronutrients and Docosahexaenoic Acid Supplementation during Pregnancy: A Randomized Controlled Study. Nutrients, 2020. Nutrients 2020, 12(8), 2432; https://doi.org/10.3390/nu12082432
  26. Maternal Postpartum Micronutrient Supplementation and Infant Development. Global Alliance for Infant and Maternal Health Research, Brown University. https://globalaim.med.brown.edu/research/maternal-postpartum-micronutrient-supplementation-and-infant-development
  27. Nafrialdi, N., & Suyatna, F. D. 2024. Pharmacokinetic Study of HY-FOLIC® and Folic Acid in Healthy Volunteers. International Journal of Applied Pharmaceutics, 64–68. https://doi.org/10.22159/ijap.2024v16i6.51874
  28. Obeid, R., et. Al. 2013. Is 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects?. J. Perinat. Med. 2013; 41(5): 469–483. DOI 10.1515/jpm-2012-0256.
  29. Obeid, R., et al. 2020. Pharmacokinetics of Sodium and Calcium Salts of (6S)-5-Methyltetrahydrofolic Acid Compared to Folic Acid and Indirect Comparison of the Two Salts. Nutrients 2020, 12, 3623; doi:10.3390/nu12123623.
  30. Obeid, R., Holzgreve, W., & Pietrzik, K. 2013. Is 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects? Journal of Perinatal Medicine, 41(5), 469–483. https://doi.org/10.1515/jpm-2012-0256
  31. Obeid, R., Schön, C., Pietrzik, K., et. al. 2020. Pharmacokinetics of sodium and calcium salts of (6S)-5-Methyltetrahydrofolic acid compared to folic acid and indirect comparison of the two salts. Nutrients, 12(12), 3623. https://doi.org/10.3390/nu12123623
  32. Pfeiffer, C. M., Sternberg, M. R., Fazili, Z., et al. 2015. Folate status and concentrations of serum folate forms in the US population: National Health and Nutrition Examination Survey 2011–2. British Journal of Nutrition, 113(12), 1965–1977. https://doi.org/10.1017/s0007114515001142
  33. Pietrzik, K., Bailey, L., Shane, B. 2010. Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics. Review Clin Pharmacokinet 2010 Aug;49(8):535-48 doi: 10.2165/11532990-000000000-00000
  34. Richmond, R. C., Sharp, G. C., Herbert, G., et al. 2018. The long-term impact of folic acid in pregnancy on offspring DNA methylation: follow-up of the Aberdeen Folic Acid Supplementation Trial (AFAST). International Journal of Epidemiology, 47(3), 928–937. https://doi.org/10.1093/ije/dyy032
  35. Rubini M., et al. 2024. Is there a multidisciplinary role for 5-methyltetrahydrofolate? The obstetric evidence in perspective. European Review for Medical and Pharmacological Sciences. 2024; 28: 3934-3945.
  36. Scaglione F, Panzavolta G. 2014. Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. Xenobiotica, 44(5):480-488. doi:10.3109/00498254.2013.845705
  37. Servy EJ, Jacquesson-Fournols L, Cohen M, Menezo YJR. 2018. MTHFR isoform carriers. 5-MTHF (5-methyltetrahydrofolate) vs folic acid: a key to pregnancy outcome: a case series. Journal of Assisted Reproduction and Genetics, 35(8):1431-1435. doi:10.1007/s10815-018-1225-2
  38. Venn, B. J., Green, T. J., Moser, R., et al. 2003. Comparison of the effect of low-dose supplementation with l-5-methyltetrahydrofolate or folic acid on plasma homocysteine: a randomized placebo-controlled study. American Journal of Clinical Nutrition, 77(3), 658–662. https://doi.org/10.1093/ajcn/77.3.658
  39. William A, Lachat C., et. Al. 2025. Long-Term Effects of Multiple-Micronutrient Supplementation During Pregnancy, Lactation, and Early Childhood on the Cognitive Development of Children Aged 4–14 Years: A Systematic Review of Randomized Controlled Trials. Nutrients 2025, 17(24), 3966; https://doi.org/10.3390/nu17243966.
  40. Wusigale, & Liang, L. 2020. Folates: Stability and interaction with biological molecules. Journal of Agriculture and Food Research, 2, 100039. https://doi.org/10.1016/j.jafr.2020.100039
  41. Zimmermann M B. 2009. Iodine deficiency in pregnancy and the effects of maternal iodine supplementation on the offspring: a review. American Journal of Clinical Nutrition.